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The assay chemistry includes dUTP and is compatible with UNG (uracil-N-glycosylase) treatment to prevent carry-over contamination
Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification
The WD40 group is a large family of proteins
cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits
Multiple transcript variants encoding different isoforms have been found for this gene
CCDC134 rabbit polyclonal antibody Standard PCR Reagents The assay chemistry includes dUTPSpecification Full name CCDC134 rabbit polyclonal antibody Alternative names 50 l 100 l Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background In extracellular secreted form, promotes proliferation and activation of CD8+ T cells, suggesting a cytokine like function (PubMed: 25125657). Enhances cytotoxic anti tumor activity of CD8+ T cells (PubMed: 25125657). May inhibit ERK and JNK signaling
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